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Importin 5 抗体

IPO5 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262636
发货至: 中国
  • 抗原 See all Importin 5 (IPO5) 抗体
    Importin 5 (IPO5)
    适用
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    人, 大鼠, 小鼠
    宿主
    • 37
    • 4
    克隆类型
    • 39
    • 2
    多克隆
    标记
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    This Importin 5 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 11
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性
    IPO5 Antibody detects endogenous levels of total IPO5
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human IPO5
    亚型
    IgG
    Top Product
    Discover our top product IPO5 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    Importin 5 (IPO5)
    别名
    IPO5 (IPO5 产品)
    别名
    IPO5 antibody, RANBP5 antibody, IMB3 antibody, KPNB3 antibody, Pse1 antibody, imp5 antibody, 1110011C18Rik antibody, 5730478E03Rik antibody, AA409333 antibody, C76941 antibody, Kpnb3 antibody, Ranbp5 antibody, importin 5 antibody, IPO5 antibody, Ipo5 antibody
    背景

    Description: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. Binds to CPEB3 and mediates its nuclear import following neuronal stimulation (By similarity). In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev.

    Gene: IPO5

    分子量
    123kDa
    基因ID
    3843
    UniProt
    O00410
    途径
    Protein targeting to Nucleus
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