电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Importin 4 抗体 (Internal Region)

IPO4 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262635
发货至: 中国
  • 抗原 See all Importin 4 (IPO4) 抗体
    Importin 4 (IPO4)
    抗原表位
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 19
    克隆类型
    • 19
    多克隆
    标记
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Importin 4 antibody is un-conjugated
    应用范围
    • 9
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    IPO4 Antibody detects endogenous levels of total IPO4.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human IPO4, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product IPO4 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Importin 4 (IPO4)
    别名
    IPO4 (IPO4 产品)
    别名
    Imp4 antibody, 8430408O15Rik antibody, AA409693 antibody, Imp4a antibody, RanBP4 antibody, importin 4 antibody, IPO4 antibody, Ipo4 antibody
    背景

    Description: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.

    Gene: IPO4

    分子量
    118 kDa
    基因ID
    79711
    UniProt
    Q8TEX9
    途径
    Protein targeting to Nucleus
You are here:
客服