NOS2 抗体 (C-Term)
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- 抗原 See all NOS2 抗体
- NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NOS2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- INOS Antibody detects endogenous levels of total iNOS.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human iNOS, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NOS2 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
- 别名
- NOS2 (NOS2 产品)
- 别名
- HEP-NOS antibody, INOS antibody, NOS antibody, NOS2A antibody, NOS-II antibody, Nos-2 antibody, Nos2a antibody, i-NOS antibody, iNOS antibody, iNos antibody, NOS2a antibody, NOS2 antibody, BmNOS2 antibody, Nsl antibody, nos2 antibody, nitric oxide synthase 2 antibody, nitric oxide synthase 2, inducible antibody, inducible nitric oxide synthase antibody, inducible nitric-oxide synthase antibody, nanos C2HC-type zinc finger 2 antibody, NOS2 antibody, Nos2 antibody, nos2 antibody, LOC396821 antibody, NANOS2 antibody
- 背景
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Description: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7531687, PubMed:7544004). In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on 'Cys-247' implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (PubMed:25417112). Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (PubMed:19688109).
Gene: NOS2
- 分子量
- 130kDa
- 基因ID
- 4843
- UniProt
- P35228
- 途径
- Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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