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IL28A 抗体 (N-Term)

IL28A 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262560
发货至: 中国
  • 抗原 See all IL28A 抗体
    IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))
    抗原表位
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 34
    • 17
    • 12
    • 12
    • 12
    • 1
    宿主
    • 27
    • 7
    • 2
    克隆类型
    • 27
    • 9
    多克隆
    标记
    • 16
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL28A antibody is un-conjugated
    应用范围
    • 26
    • 11
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    IL28A Antibody detects endogenous levels of total IL28A.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human IL28A, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product IL28A Primary Antibody
  • 应用备注
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))
    别名
    IFNL2 (IL28A 产品)
    别名
    EG330496 antibody, IL-28A antibody, Il28a antibody, IL28A antibody, interferon lambda 2 antibody, Ifnl2 antibody, IFNL2 antibody
    背景

    Description: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

    Gene: IFNL2

    分子量
    22 kDa
    基因ID
    282616
    UniProt
    Q8IZJ0
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