IL1F9 抗体 (N-Term)
-
- 抗原 See all IL1F9 抗体
- IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This IL1F9 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
- IL1F9 Antibody detects endogenous levels of total IL1F9.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human IL1F9, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product IL1F9 Primary Antibody
-
-
- 应用备注
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
- 别名
- IL36G (IL1F9 产品)
- 别名
- IL-1F9 antibody, IL-1H1 antibody, IL-1RP2 antibody, IL1E antibody, IL1F9 antibody, IL1H1 antibody, IL1RP2 antibody, Il36g antibody, Il1f9 antibody, RGD1563019 antibody, IL36G antibody, interleukin 36 gamma antibody, interleukin 1 family, member 9 antibody, interleukin 36, gamma antibody, interleukin-36 gamma antibody, IL36G antibody, Il1f9 antibody, Il36g antibody, LOC100065031 antibody
- 背景
-
Description: Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response, similar to the IL-1 system with which it shares the coreceptor IL1RAP. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation. In cultured keratinocytes induces the expression of macrophage, T-cell, and neutrophil chemokines, such as CCL3, CCL4, CCL5, CCL2, CCL17, CCL22, CL20, CCL5, CCL2, CCL17, CCL22, CXCL8, CCL20 and CXCL1, also stimulates its own expression and that of the prototypic cutaneous proinflammatory parameters TNF-alpha, S100A7/psoriasin and inducible NOS. May play a role in proinflammatory responses during particular neutrophilic airway inflammation: activates mitogen-activated protein kinases and NF-kappa B in primary lung fibroblasts, and stimulates the expression of IL-8 and CXCL3 and Th17 chemokine CCL20 in lung fibroblasts. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus.
Gene: IL36G
- 分子量
- 19 kDa
- 基因ID
- 56300
- UniProt
- Q9NZH8
-