IGHG1 抗体
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- 抗原 See all IGHG1 抗体
- IGHG1 (Immunoglobulin Heavy Constant gamma 1 (G1m Marker) (IGHG1))
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IGHG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- IGHG1 Antibody detects endogenous levels of total IGHG1
- 交叉反应
- 人
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human IGHG1
- 亚型
- IgG
- Top Product
- Discover our top product IGHG1 Primary Antibody
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- 应用备注
- WB 1:1000-3000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- IGHG1 (Immunoglobulin Heavy Constant gamma 1 (G1m Marker) (IGHG1))
- 别名
- IGHG1 (IGHG1 产品)
- 别名
- RGD1359539 antibody, IgG1 antibody, Igh-4 antibody, VH7183 antibody, immunoglobulin heavy constant gamma 1 antibody, immunoglobulin heavy constant gamma 1 (G1m marker) antibody, Ighg1 antibody, IGHG1 antibody
- 背景
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Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Gene: IGHG1
- UniProt
- P01857
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