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IFITM3 抗体 (N-Term)

IFITM3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262457
发货至: 中国
  • 抗原 See all IFITM3 抗体
    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
    抗原表位
    • 8
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 37
    • 5
    • 4
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 28
    • 6
    • 3
    克隆类型
    • 33
    • 4
    多克隆
    标记
    • 25
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFITM3 antibody is un-conjugated
    应用范围
    • 27
    • 18
    • 10
    • 9
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    IFITM3 Antibody detects endogenous levels of total IFITM3.
    预测反应
    Pig,Sheep
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human IFITM3, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product IFITM3 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
    别名
    IFITM3 (IFITM3 产品)
    别名
    1110004C05Rik antibody, Cd225 antibody, Cdw217 antibody, DSPA2b antibody, Fgls antibody, IP15 antibody, mil-1 antibody, 1-8U antibody, rat8 antibody, Interferon-induced transmembrane protein 3 antibody, interferon induced transmembrane protein 3 antibody, ifm3 antibody, Ifitm3 antibody, IFITM3 antibody
    背景

    Description: IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the  pH in phagocytic endosomes thus establishing an antiviral state.

    Gene: IFITM3

    分子量
    15 kDa
    基因ID
    10410
    UniProt
    Q01628
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