HUS1 抗体 (Internal Region)
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- 抗原 See all HUS1 抗体
- HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
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抗原表位
- Internal Region
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HUS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- HUS1 Antibody detects endogenous levels of total HUS1.
- 预测反应
- Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human HUS1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product HUS1 Primary Antibody
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anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) antibody
HUS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (Center) antibodyHUS1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) antibodyHUS1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) antibodyHUS1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 2-280) antibodyHUS1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) antibodyHUS1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) antibodyHUS1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) antibodyHUS1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) antibodyHUS1 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 2B12 unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) antibodyHUS1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
- 别名
- HUS1 (HUS1 产品)
- 别名
- hHUS1 antibody, mHus1 antibody, XHus1 antibody, hus1 antibody, HUS1 checkpoint clamp component antibody, checkpoint clamp complex protein Hus1 antibody, HUS1 checkpoint clamp component L homeolog antibody, HUS1 antibody, Hus1 antibody, hus1 antibody, hus1.L antibody
- 背景
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Description: Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds, endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths, and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase.
Gene: HUS1
- 分子量
- 31kDa
- 基因ID
- 3364
- UniProt
- O60921
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