HSPA1L 抗体 (Internal Region)
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- 抗原 See all HSPA1L 抗体
- HSPA1L (Heat Shock 70kDa Protein 1-Like (HSPA1L))
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抗原表位
- Internal Region
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSPA1L antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- HSPA1L Antibody detects endogenous levels of total HSPA1L.
- 预测反应
- Pig,Bovine,Horse,Sheep,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human HSPA1L, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product HSPA1L Primary Antibody
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anti-Heat Shock 70kDa Protein 1-Like (HSPA1L) (AA 1-641) antibody
HSPA1L 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 1-Like (HSPA1L) (AA 1-641) antibodyHSPA1L 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 1-Like (HSPA1L) (AA 561-641) antibodyHSPA1L 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 7H6 unconjugated
anti-Heat Shock 70kDa Protein 1-Like (HSPA1L) (AA 1-641) antibodyHSPA1L 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 2-1# unconjugated
anti-Heat Shock 70kDa Protein 1-Like (HSPA1L) (AA 342-641) antibodyHSPA1L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 1-Like (HSPA1L) (AA 420-641) antibodyHSPA1L 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 1-Like (HSPA1L) (AA 1-641) antibodyHSPA1L 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 1-Like (HSPA1L) (AA 1-641) antibodyHSPA1L 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 1-Like (HSPA1L) antibodyHSPA1L 适用: 人 WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal unconjugated
anti-Heat Shock 70kDa Protein 1-Like (HSPA1L) antibodyHSPA1L 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- HSPA1L (Heat Shock 70kDa Protein 1-Like (HSPA1L))
- 别名
- HSPA1L (HSPA1L 产品)
- 别名
- Hsc70t antibody, Msh5 antibody, HSPA1L antibody, hspa1l antibody, MGC147483 antibody, Hsp70-3 antibody, HSP70-1L antibody, HSP70-HOM antibody, HSP70T antibody, hum70t antibody, heat shock 70kDa protein 1-like antibody, heat shock protein 1-like antibody, heat shock 70 kDa protein 1-like antibody, heat shock protein family A (Hsp70) member 1 like antibody, HSPA1L antibody, Hspa1l antibody, LOC471967 antibody, hspa1l antibody, LOC474850 antibody, LOC102177850 antibody, LOC100050904 antibody
- 背景
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Description: Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release (PubMed:26865365). Positive regulator of PRKN translocation to damaged mitochondria (PubMed:24270810).
Gene: HSPA1L
- 分子量
- 70kDa
- 基因ID
- 3305
- UniProt
- P34931
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