CBX3 抗体 (Internal Region)
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- 抗原 See all CBX3 抗体
- CBX3 (Chromobox Homolog 3 (CBX3))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBX3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- HP1 gamma Antibody detects endogenous levels of total HP1 gamma.
- 预测反应
- Pig,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human HP1 gamma, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CBX3 Primary Antibody
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anti-Chromobox Homolog 3 (CBX3) (Internal Region) antibody
Verified CBX3 适用: 人, 小鼠 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6D1C4 unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G12-1D9 unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 1-183) antibodyCBX3 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (AA 2-183) antibodyCBX3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) antibodyCBX3 适用: 人, 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) antibodyCBX3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 3 (CBX3) (Middle Region) antibodyCBX3 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CBX3 (Chromobox Homolog 3 (CBX3))
- 别名
- CBX3 (CBX3 产品)
- 别名
- HECH antibody, HP1-GAMMA antibody, HP1Hs-gamma antibody, Hp1-gamma antibody, HP1g antibody, M32 antibody, cbx3 antibody, cbx3a antibody, xhp1g antibody, wu:fb61b02 antibody, zgc:153397 antibody, chromobox 3 antibody, chromobox 3 L homeolog antibody, chromobox protein homolog 3 pseudogene antibody, chromobox homolog 3a (HP1 gamma homolog, Drosophila) antibody, CBX3 antibody, Cbx3 antibody, cbx3.L antibody, LOC100355282 antibody, cbx3a antibody
- 背景
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Description: Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1. Mediates the recruitement of NIPBL to sites of DNA damage at double-strand breaks (DSBs) (PubMed:28167679).
Gene: CBX3
- 分子量
- 22kDa
- 基因ID
- 11335
- UniProt
- Q13185
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