HNRNPA2B1 抗体 (N-Term)
Quick Overview for HNRNPA2B1 抗体 (N-Term) (ABIN6262328)
抗原
See all HNRNPA2B1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- HnRNP A2/B1 Antibody detects endogenous levels of total hnRNP A2/B1.
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预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human hnRNP A2/B1, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) (AA 1-180) antibody
HNRNPA2B1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) (AA 1-249) antibodyHNRNPA2B1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G12-6C5 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) (Internal Region) antibodyVerified HNRNPA2B1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) antibodyHNRNPA2B1 适用: 人, 小鼠, 大鼠, Pig, 小鸡 WB, IF, ICC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal DP3B3 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) (AA 21-103) antibodyHNRNPA2B1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) (AA 1-249) antibodyHNRNPA2B1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) (AA 1-249) antibodyHNRNPA2B1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G11-6A7 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) antibodyHNRNPA2B1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) (N-Term) antibodyHNRNPA2B1 适用: 人, 小鼠, 大鼠, Pig, 犬, 马, 兔, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) (N-Term) antibodyHNRNPA2B1 适用: 人, 小鼠, 大鼠, Pig, 犬, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- HNRNPA2B1 (Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1))
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别名
- HNRNPA2B1
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背景
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Description: Heterogeneous nuclear ribonucleoprotein (hnRNP) that associates with nascent pre-mRNAs, packaging them into hnRNP particles. The hnRNP particle arrangement on nascent hnRNA is non-random and sequence-dependent and serves to condense and stabilize the transcripts and minimize tangling and knotting. Packaging plays a role in various processes such as transcription, pre-mRNA processing, RNA nuclear export, subcellular location, mRNA translation and stability of mature mRNAs (PubMed:19099192). Forms hnRNP particles with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus. Involved in transport of specific mRNAs to the cytoplasm in oligodendrocytes and neurons: acts by specifically recognizing and binding the A2RE (21 nucleotide hnRNP A2 response element) or the A2RE11 (derivative 11 nucleotide oligonucleotide) sequence motifs present on some mRNAs, and promotes their transport to the cytoplasm (PubMed:10567417). Specifically binds single-stranded telomeric DNA sequences, protecting telomeric DNA repeat against endonuclease digestion (By similarity). Also binds other RNA molecules, such as primary miRNA (pri-miRNAs): acts as a nuclear 'reader' of the N6-methyladenosine (m6A) mark by specifically recognizing and binding a subset of nuclear m6A-containing pri-miRNAs. Binding to m6A-containing pri-miRNAs promotes pri-miRNA processing by enhancing binding of DGCR8 to pri-miRNA transcripts (PubMed:26321680). Involved in miRNA sorting into exosomes following sumoylation, possibly by binding (m6A)-containing pre-miRNAs (PubMed:24356509). Acts as a regulator of efficiency of mRNA splicing, possibly by binding to m6A-containing pre-mRNAs (PubMed:26321680).
Gene: HNRNPA2B1
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分子量
- 37kDa
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基因ID
- 3181
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UniProt
- P22626
抗原
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