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RBMX 抗体 (N-Term)

RBMX 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262320
发货至: 中国
  • 抗原 See all RBMX 抗体
    RBMX (RNA Binding Motif Protein, X-Linked (RBMX))
    抗原表位
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 22
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 22
    克隆类型
    • 22
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RBMX antibody is un-conjugated
    应用范围
    • 15
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    HnRNP G Antibody detects endogenous levels of total hnRNP G.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human hnRNP G, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    RBMX (RNA Binding Motif Protein, X-Linked (RBMX))
    别名
    RBMX (RBMX 产品)
    别名
    hnRNP G antibody, HNRNPG antibody, HNRPG antibody, RBMXP1 antibody, RBMXRT antibody, RNMX antibody, hnRNP-G antibody, fc66e11 antibody, wu:fb37c07 antibody, wu:fc66e11 antibody, hnrnpg antibody, hnrpg antibody, rbmxp1 antibody, rbmxrt antibody, rnmx antibody, RBMXL1 antibody, RNA binding motif protein, X chromosome antibody, RNA binding motif protein, X-linked antibody, RNA binding motif protein, X-linked S homeolog antibody, Rbmx antibody, RBMX antibody, rbmx antibody, rbmx.S antibody
    背景

    Description: RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes. Implicated in tissue-specific regulation of gene transcription and alternative splicing of several pre-mRNAs. Binds to and stimulates transcription from the tumor suppressor TXNIP gene promoter, may thus be involved in tumor suppression. When associated with SAFB, binds to and stimulates transcription from the SREBF1 promoter. Associates with nascent mRNAs transcribed by RNA polymerase II. Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection. Can either activate or suppress exon inclusion, acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN2. Represses the splicing of MAPT/Tau exon 10. Binds preferentially to single-stranded 5'-CC[A/C]-rich RNA sequence motifs localized in a single-stranded conformation, probably binds RNA as a homodimer. Binds non-specifically to pre-mRNAs. Plays also a role in the cytoplasmic TNFR1 trafficking pathways, promotes both the IL-1-beta-mediated inducible proteolytic cleavage of TNFR1 ectodomains and the release of TNFR1 exosome-like vesicles to the extracellular compartment.

    Gene: RBMX

    分子量
    42 kDa
    基因ID
    27316
    UniProt
    P38159
    途径
    Chromatin Binding, Ribonucleoprotein Complex Subunit Organization
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