RBMX 抗体 (N-Term)
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- 抗原 See all RBMX 抗体
- RBMX (RNA Binding Motif Protein, X-Linked (RBMX))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RBMX antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- HnRNP G Antibody detects endogenous levels of total hnRNP G.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human hnRNP G, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- RBMX (RNA Binding Motif Protein, X-Linked (RBMX))
- 别名
- RBMX (RBMX 产品)
- 别名
- hnRNP G antibody, HNRNPG antibody, HNRPG antibody, RBMXP1 antibody, RBMXRT antibody, RNMX antibody, hnRNP-G antibody, fc66e11 antibody, wu:fb37c07 antibody, wu:fc66e11 antibody, hnrnpg antibody, hnrpg antibody, rbmxp1 antibody, rbmxrt antibody, rnmx antibody, RBMXL1 antibody, RNA binding motif protein, X chromosome antibody, RNA binding motif protein, X-linked antibody, RNA binding motif protein, X-linked S homeolog antibody, Rbmx antibody, RBMX antibody, rbmx antibody, rbmx.S antibody
- 背景
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Description: RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes. Implicated in tissue-specific regulation of gene transcription and alternative splicing of several pre-mRNAs. Binds to and stimulates transcription from the tumor suppressor TXNIP gene promoter, may thus be involved in tumor suppression. When associated with SAFB, binds to and stimulates transcription from the SREBF1 promoter. Associates with nascent mRNAs transcribed by RNA polymerase II. Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection. Can either activate or suppress exon inclusion, acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN2. Represses the splicing of MAPT/Tau exon 10. Binds preferentially to single-stranded 5'-CC[A/C]-rich RNA sequence motifs localized in a single-stranded conformation, probably binds RNA as a homodimer. Binds non-specifically to pre-mRNAs. Plays also a role in the cytoplasmic TNFR1 trafficking pathways, promotes both the IL-1-beta-mediated inducible proteolytic cleavage of TNFR1 ectodomains and the release of TNFR1 exosome-like vesicles to the extracellular compartment.
Gene: RBMX
- 分子量
- 42 kDa
- 基因ID
- 27316
- UniProt
- P38159
- 途径
- Chromatin Binding, Ribonucleoprotein Complex Subunit Organization
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