HMGB3 抗体 (Internal Region)
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- 抗原 See all HMGB3 抗体
- HMGB3 (High Mobility Group Box 3 (HMGB3))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HMGB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- HMGB3 Antibody detects endogenous levels of total HMGB3.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human HMGB3, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product HMGB3 Primary Antibody
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anti-High Mobility Group Box 3 (HMGB3) (AA 1-103) antibody
HMGB3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 62-95), (N-Term) antibodyHMGB3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) antibodyHMGB3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 1-200) antibodyHMGB3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (C-Term) antibodyHMGB3 适用: 人, 小鼠, 大鼠, Cow, 马, 犬, 兔, Pig, 豚鼠, 斑马鱼, 猴, 小鸡, Hamster, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 150-200) antibodyHMGB3 适用: 人, 小鼠, Cow, 马, 犬, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 14-176) antibodyHMGB3 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) antibodyHMGB3 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 1-50) antibodyHMGB3 适用: 人, 小鼠, 大鼠, Cow, 马, Opossum WB 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (N-Term) antibodyHMGB3 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, Pig, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- HMGB3 (High Mobility Group Box 3 (HMGB3))
- 别名
- HMGB3 (HMGB3 产品)
- 别名
- HMG-2a antibody, HMG-4 antibody, HMG2A antibody, HMG4 antibody, Hmg2a antibody, Hmg4 antibody, RGD1564407 antibody, hmgb3 antibody, MGC54022 antibody, Xhmgb3 antibody, MGC88931 antibody, fa19b06 antibody, fj43d02 antibody, wu:fa19b06 antibody, wu:fj43d02 antibody, zgc:112073 antibody, HMGB3 antibody, NFD03 antibody, NFD3 antibody, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR antibody, high mobility group B3 antibody, HMG-1 antibody, HMG2a antibody, HMGB1 antibody, high mobility group box 3 antibody, high mobility group box 3b antibody, high mobility group box 3 S homeolog antibody, high mobility group protein antibody, high mobility group B3 antibody, High mobility group protein B3 antibody, HMGB3 antibody, Hmgb3 antibody, hmgb3 antibody, hmgb3b antibody, hmgb3.S antibody
- 背景
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Description: Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (By similarity).
Gene: HMGB3
- 分子量
- 23 kDa
- 基因ID
- 3149
- UniProt
- O15347
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