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HECTD1 抗体

HECTD1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262200
发货至: 中国
  • 抗原 See all HECTD1 抗体
    HECTD1 (HECT Domain Containing 1 (HECTD1))
    适用
    • 35
    • 24
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    人, 小鼠, 大鼠
    宿主
    • 31
    • 5
    克隆类型
    • 32
    • 4
    多克隆
    标记
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    This HECTD1 antibody is un-conjugated
    应用范围
    • 13
    • 12
    • 7
    • 5
    • 4
    • 4
    • 3
    Western Blotting (WB), ELISA
    特异性
    HECTD1 Antibody detects endogenous levels of total HECTD1
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human HECTD1
    亚型
    IgG
    Top Product
    Discover our top product HECTD1 Primary Antibody
  • 应用备注
    WB 1:1000-3000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    HECTD1 (HECT Domain Containing 1 (HECTD1))
    别名
    HECTD1 (HECTD1 产品)
    别名
    RGD1561653 antibody, HECTD1 antibody, hectd1 antibody, MGC172681 antibody, A630086P08Rik antibody, AI844876 antibody, b2b327Clo antibody, opm antibody, HECT domain E3 ubiquitin protein ligase 1 antibody, HECT domain containing E3 ubiquitin protein ligase 1 antibody, Hectd1 antibody, HECTD1 antibody, hectd1 antibody
    背景

    Description: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure.

    Gene: HECTD1

    分子量
    289kDa
    基因ID
    25831
    UniProt
    Q9ULT8
    途径
    Tube Formation, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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