HECTD1 抗体
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- 抗原 See all HECTD1 抗体
- HECTD1 (HECT Domain Containing 1 (HECTD1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HECTD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- HECTD1 Antibody detects endogenous levels of total HECTD1
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human HECTD1
- 亚型
- IgG
- Top Product
- Discover our top product HECTD1 Primary Antibody
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- 应用备注
- WB 1:1000-3000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- HECTD1 (HECT Domain Containing 1 (HECTD1))
- 别名
- HECTD1 (HECTD1 产品)
- 别名
- RGD1561653 antibody, HECTD1 antibody, hectd1 antibody, MGC172681 antibody, A630086P08Rik antibody, AI844876 antibody, b2b327Clo antibody, opm antibody, HECT domain E3 ubiquitin protein ligase 1 antibody, HECT domain containing E3 ubiquitin protein ligase 1 antibody, Hectd1 antibody, HECTD1 antibody, hectd1 antibody
- 背景
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Description: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure.
Gene: HECTD1
- 分子量
- 289kDa
- 基因ID
- 25831
- UniProt
- Q9ULT8
- 途径
- Tube Formation, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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