HCFC1 抗体 (N-Term)
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- 抗原 See all HCFC1 抗体
- HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HCFC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
- HCFC1 Antibody detects endogenous levels of total HCFC1.
- 预测反应
- Pig,Bovine,Horse,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human HCFC1, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product HCFC1 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))
- 别名
- HCFC1 (HCFC1 产品)
- 别名
- CFF antibody, HCF-1 antibody, HCF1 antibody, HFC1 antibody, MRX3 antibody, VCAF antibody, AW060991 antibody, HCF antibody, RGD1563804 antibody, fc61g09 antibody, hcfc1 antibody, im:7159458 antibody, wu:fc61g09 antibody, wu:fj40c12 antibody, HCFC1 antibody, host cell factor C1 antibody, host cell factor C1a antibody, host cell factor antibody, host cell factor C1 (VP16-accessory protein) antibody, HCFC1 antibody, Hcfc1 antibody, hcfc1a antibody, LOC5571204 antibody, CpipJ_CPIJ014908 antibody
- 背景
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Description: Involved in control of the cell cycle (PubMed:10629049, PubMed:10779346, PubMed:15190068, PubMed:16624878, PubMed:23629655). Also antagonizes transactivation by ZBTB17 and GABP2, represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300 (PubMed:10675337, PubMed:12244100). Coactivator for EGR2 and GABP2 (PubMed:12244100, PubMed:14532282). Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription, respectively) together (PubMed:12670868). Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1 (PubMed:20200153). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Recruits KMT2E/MLL5 to E2F1 responsive promoters promoting transcriptional activation and thereby facilitates G1 to S phase transition (PubMed:23629655).
Gene: HCFC1
- 分子量
- 209kDa
- 基因ID
- 3054
- UniProt
- P51610
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