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Glutamate Receptor 3 抗体

GRIA3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262082
发货至: 中国
  • 抗原 See all Glutamate Receptor 3 (GRIA3) 抗体
    Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))
    适用
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    人, 大鼠, 小鼠
    宿主
    • 54
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    克隆类型
    • 55
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    多克隆
    标记
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    This Glutamate Receptor 3 antibody is un-conjugated
    应用范围
    • 30
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    GRIA3 Antibody detects endogenous levels of total GRIA3
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human GRIA3
    亚型
    IgG
    Top Product
    Discover our top product GRIA3 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))
    别名
    GRIA3 (GRIA3 产品)
    背景

    Description: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

    Gene: GRIA3

    分子量
    101kDa
    基因ID
    2892
    UniProt
    P42263
    途径
    PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane
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