O3FAR1 抗体 (Internal Region)
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- 抗原 See all O3FAR1 抗体
- O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This O3FAR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- GPR120 Antibody detects endogenous levels of total GPR120.
- 预测反应
- Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human GPR120, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product O3FAR1 Primary Antibody
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anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (N-Term) antibody
O3FAR1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) antibodyO3FAR1 适用: 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (AA 22-36), (Extracellular), (N-Term) antibodyO3FAR1 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (Internal Region) antibodyO3FAR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (C-Term) antibodyO3FAR1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (AA 1-71) antibodyO3FAR1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (AA 247-258) antibodyO3FAR1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (Internal Region) antibodyVerified O3FAR1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (AA 243-292) antibodyO3FAR1 适用: 人, 小鼠, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))
- 别名
- FFAR4 (O3FAR1 产品)
- 别名
- BMIQ10 antibody, GPR120 antibody, GPR129 antibody, GT01 antibody, O3FAR1 antibody, PGR4 antibody, AI552415 antibody, Gpr120 antibody, Gpr129 antibody, KPG_013 antibody, O3far1 antibody, Pgr4 antibody, free fatty acid receptor 4 antibody, phosphodiesterase 6C antibody, FFAR4 antibody, Ffar4 antibody, PDE6C antibody
- 背景
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Description: Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.
Gene: FFAR4
- 分子量
- 42 kDa
- 基因ID
- 338557
- UniProt
- Q5NUL3
- 途径
- Hormone Transport
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