ARHGEF25/GEFT 抗体 (Internal Region)
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- 抗原 See all ARHGEF25/GEFT (ARHGEF25) 抗体
- ARHGEF25/GEFT (ARHGEF25) (Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25))
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抗原表位
- Internal Region
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适用
- 大鼠, 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARHGEF25/GEFT antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- GEFT Antibody detects endogenous levels of total GEFT.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human GEFT, corresponding to a region within the internal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ARHGEF25/GEFT (ARHGEF25) (Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25))
- 别名
- ARHGEF25 (ARHGEF25 产品)
- 别名
- GEFT antibody, p63RhoGEF antibody, 2410008H17Rik antibody, D10Ertd610e antibody, Geft antibody, Rho guanine nucleotide exchange factor 25 antibody, Rho guanine nucleotide exchange factor (GEF) 25 antibody, ARHGEF25 antibody, Arhgef25 antibody
- 背景
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Description: May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved in skeletal myogenesis (By similarity).
Gene: ARHGEF25
- 分子量
- 64 kDa
- 基因ID
- 115557
- UniProt
- Q86VW2
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