GAB2 抗体 (C-Term)
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- 抗原 See all GAB2 抗体
- GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GAB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- Gab2 Antibody detects endogenous levels of total Gab2.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Gab2, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product GAB2 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
- 别名
- GAB2 (GAB2 产品)
- 别名
- GAB2 antibody, AI463667 antibody, D130058I17Rik antibody, p97 antibody, GRB2 associated binding protein 2 antibody, GRB2-associated binding protein 2 antibody, growth factor receptor bound protein 2-associated protein 2 antibody, GAB2 antibody, gab2 antibody, Gab2 antibody
- 背景
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Description: Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Gene: GAB2
- 分子量
- 97kDa
- 基因ID
- 9846
- UniProt
- Q9UQC2
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect
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