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c-FOS 抗体 (N-Term)

c-Fos 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261783
发货至: 中国
  • 抗原 See all c-FOS (c-Fos) 抗体
    c-FOS (c-Fos) (c-Fos)
    抗原表位
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    N-Term
    适用
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    人, 小鼠, 大鼠
    宿主
    • 201
    • 39
    • 6
    • 1
    克隆类型
    • 204
    • 42
    多克隆
    标记
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    This c-FOS antibody is un-conjugated
    应用范围
    • 202
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
    特异性
    C-Fos Antibody detects endogenous levels of total c-Fos.
    预测反应
    Pig,Bovine,Horse,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human c-Fos, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product c-Fos Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IP, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    c-FOS (c-Fos) (c-Fos)
    别名
    FOS (c-Fos 产品)
    别名
    AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody
    背景

    Description: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

    Gene: FOS

    分子量
    50 kDa
    基因ID
    2353
    UniProt
    P01100
    途径
    S100 Proteins
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