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FER 抗体 (C-Term)

FER 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261711
发货至: 中国
  • 抗原 See all FER 抗体
    FER (FER Tyrosine Kinase (FER))
    抗原表位
    • 26
    • 15
    • 14
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 74
    • 69
    • 15
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 92
    • 10
    克隆类型
    • 92
    • 10
    多克隆
    标记
    • 42
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This FER antibody is un-conjugated
    应用范围
    • 80
    • 36
    • 26
    • 26
    • 14
    • 13
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    FER Antibody detects endogenous levels of total FER.
    预测反应
    Pig,Bovine,Horse,Sheep,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human FER, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product FER Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    FER (FER Tyrosine Kinase (FER))
    别名
    FER (FER 产品)
    别名
    FerT antibody, PPP1R74 antibody, TYK3 antibody, Fer antibody, Flk antibody, Flk_retired antibody, AV082135 antibody, C330004K01Rik antibody, Fert antibody, FER tyrosine kinase antibody, fer (fms/fps related) protein kinase antibody, FER antibody, Fer antibody
    背景

    Description: Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase. Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Plays a role in the regulation of mast cell degranulation. Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide (LPS). Plays a role in synapse organization, trafficking of synaptic vesicles, the generation of excitatory postsynaptic currents and neuron-neuron synaptic transmission. Plays a role in neuronal cell death after brain damage. Phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1 and PTPN11. May phosphorylate JUP and PTPN1. Can phosphorylate STAT3, but the biological relevance of this depends on cell type and stimulus.

    Gene: FER

    分子量
    85kDa
    基因ID
    2241
    UniProt
    P16591
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