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ERCC3 抗体 (N-Term)

Name: ERCC3 抗体 (N-Term)
SKU: ABIN6261590
Availability: OutOfStock

ERCC3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of COLO 320, using ERCC3 antibody. (ERCC3 抗体 (N-Term))

ABIN6276833 at 1/100 staining Mouse brain tissue by IHC-P. (ERCC3 抗体 (N-Term))

IHC

2 images

产品编号 ABIN6261590

发货至: 中国

Datasheet as PDF

抗原 See all ERCC3 抗体

ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))
抗原表位
15

2

2

2

2

2

1

1

1

1

1

1

1
N-Term
适用
46

28

16

4

4

3

3

1

1

1

1

1
人, 大鼠, 小鼠
宿主
37

8

1

1
兔
Compatible Secondaries
克隆类型
40

7
多克隆
标记
26

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This ERCC3 antibody is un-conjugated
应用范围
36

13

13

10

7

7

6

4

3

2

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

特异性

ERCC3 Antibody detects endogenous levels of total ERCC3.

预测反应

Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human ERCC3, corresponding to a region within N-terminal amino acids.

亚型

IgG
anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (AA 521-712) antibody
ERCC3 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (C-Term) antibody
ERCC3 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (AA 242-261) antibody
ERCC3 适用: 人 WB, ELISA, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 3G4 unconjugated

anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (AA 513-782) antibody
ERCC3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (AA 601-700) antibody
ERCC3 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) antibody
ERCC3 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (AA 29-128) antibody
ERCC3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (N-Term) antibody
ERCC3 适用: 人, Cow, 犬, 斑马鱼, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (AA 512-782) antibody
ERCC3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (N-Term) antibody
ERCC3 适用: 人, 大鼠, Cow, 犬, 斑马鱼, 兔, 豚鼠, Pig, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

别名

ERCC3 (ERCC3 产品)

别名

BTF2 antibody, GTF2H antibody, RAD25 antibody, TFIIH antibody, XPB antibody, BTF2 p89 antibody, Ercc-3 antibody, wu:fc25f08 antibody, ERCC excision repair 3, TFIIH core complex helicase subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 3 antibody, excision repair cross-complementation group 3 antibody, ERCC3 antibody, Ercc3 antibody, ercc3 antibody

背景

Description: ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/ERCC3, but not its helicase activity, is required for DNA opening. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. The ATP-dependent helicase activity of XPB/ERCC3 is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
Gene: ERCC3

分子量

89kDa

基因ID

2071

UniProt

P19447

途径

DNA Damage Repair