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- 抗原 See all EDEM1 抗体
- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EDEM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- EDEM1 Antibody detects endogenous levels of total EDEM1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human EDEM1, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product EDEM1 Primary Antibody
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anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 559-656) antibody
EDEM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 46-128) antibodyEDEM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 146-195) antibodyEDEM1 适用: 人, 小鼠, 兔, Cow, 猴, Pig, 豚鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (N-Term) antibodyEDEM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
- 别名
- EDEM1 (EDEM1 产品)
- 别名
- zgc:55816 antibody, edem antibody, EDEM1 antibody, EDEM antibody, A130059K23Rik antibody, mKIAA0212 antibody, RGD1563633 antibody, ER degradation enhancer, mannosidase alpha-like 1 antibody, ER degradation enhancing alpha-mannosidase like protein 1 antibody, ER degradation-enhancing alpha-mannosidase-like protein 1 antibody, ER degradation enhancing alpha-mannosidase like protein 1 L homeolog antibody, edem1 antibody, EDEM1 antibody, LOC100637820 antibody, edem1.L antibody, Edem1 antibody
- 背景
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Description: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.
Gene: EDEM1
- 分子量
- 74 kDa
- 基因ID
- 9695
- UniProt
- Q92611
- 途径
- ER-Nucleus Signaling
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