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EBI3 抗体 (N-Term)

IL-27b 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261419
发货至: 中国
  • 抗原 See all EBI3 (IL-27b) 抗体
    EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))
    抗原表位
    • 15
    • 11
    • 10
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 65
    • 17
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 60
    • 8
    • 5
    • 1
    克隆类型
    • 62
    • 12
    多克隆
    标记
    • 34
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EBI3 antibody is un-conjugated
    应用范围
    • 45
    • 31
    • 18
    • 13
    • 13
    • 9
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    EBI3 Antibody detects endogenous levels of total EBI3.
    预测反应
    Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human EBI3, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product IL-27b Primary Antibody
  • 应用备注
    WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))
    别名
    EBI3 (IL-27b 产品)
    别名
    IL-27B antibody, IL27B antibody, EBI3 antibody, il-27rb antibody, si:dkey-97a13.4 antibody, EBI-3 antibody, IL-27 antibody, Epstein-Barr virus induced 3 antibody, Epstein-Barr virus induced gene 3 antibody, EBI3 antibody, ebi3 antibody, Ebi3 antibody
    物质类
    Viral Protein
    背景

    Description: Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.

    Gene: EBI3

    分子量
    25 kDa
    基因ID
    10148
    UniProt
    Q14213
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