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DTNBP1 抗体 (C-Term)

DTNBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261377
发货至: 中国
  • 抗原 See all DTNBP1 抗体
    DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 58
    • 27
    • 26
    • 15
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 88
    • 2
    克隆类型
    • 88
    • 2
    多克隆
    标记
    • 26
    • 9
    • 9
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DTNBP1 antibody is un-conjugated
    应用范围
    • 46
    • 42
    • 29
    • 26
    • 26
    • 11
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    DTNBP1 Antibody detects endogenous levels of total DTNBP1.
    预测反应
    Bovine,Horse
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human DTNBP1, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product DTNBP1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
    别名
    DTNBP1 (DTNBP1 产品)
    别名
    5430437B18Rik antibody, AW048963 antibody, Bloc1s8 antibody, dysbindin antibody, sdy antibody, BLOC1S8 antibody, DBND antibody, HPS7 antibody, My031 antibody, SDY antibody, dtnbp1 antibody, zgc:56462 antibody, MGC83903 antibody, dbnd antibody, hps7 antibody, my031 antibody, MGC85477 antibody, DTNBP1 antibody, CG6856 antibody, Ddysb antibody, Dmel\\CG6856 antibody, si:ch211-285p6.1 antibody, dystrobrevin binding protein 1 antibody, Dysbindin antibody, dystrobrevin binding protein 1a antibody, dystrobrevin binding protein 1 L homeolog antibody, dystrobrevin binding protein 1 S homeolog antibody, dystrobrevin binding protein 1b antibody, Dtnbp1 antibody, DTNBP1 antibody, dtbp1 antibody, dtnbp1a antibody, dtnbp1.L antibody, dtnbp1.S antibody, dtnbp1 antibody, Dysb antibody, dtnbp1b antibody
    背景

    Description: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway.

    Gene: DTNBP1

    分子量
    39kDa
    基因ID
    84062
    UniProt
    Q96EV8
    途径
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling
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