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- 抗原 See all DOCK7 抗体
- DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DOCK7 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 特异性
- DOCK7 Antibody detects endogenous levels of total DOCK7.
- 预测反应
- Pig,Bovine,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human DOCK7, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product DOCK7 Primary Antibody
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anti-Dedicator of Cytokinesis 7 (DOCK7) (AA 1440-1671) antibody
DOCK7 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dedicator of Cytokinesis 7 (DOCK7) (AA 1-624) antibodyDOCK7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
- 别名
- DOCK7 (DOCK7 产品)
- 别名
- im:7145816 antibody, im:7157388 antibody, wu:fb93h07 antibody, ZIR2 antibody, 3110056M06Rik antibody, Gm430 antibody, m antibody, mKIAA1771 antibody, dedicator of cytokinesis 7 antibody, dedicator of cytokinesis protein 7 antibody, dedicator of cytokinesis 6 antibody, DOCK7 antibody, dock7 antibody, NAEGRDRAFT_56982 antibody, LOC100185115 antibody, dock6 antibody, Dock7 antibody
- 背景
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Description: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
Gene: DOCK7
- 分子量
- 242kDa
- 基因ID
- 85440
- UniProt
- Q96N67
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