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DNAJC3 抗体 (C-Term)

DNAJC3 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261337
发货至: 中国
  • 抗原 See all DNAJC3 抗体
    DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))
    抗原表位
    • 15
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 24
    • 18
    • 16
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 37
    • 3
    克隆类型
    • 38
    • 2
    多克隆
    标记
    • 12
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DNAJC3 antibody is un-conjugated
    应用范围
    • 14
    • 13
    • 13
    • 10
    • 4
    • 3
    • 3
    • 3
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    DNAJC3 Antibody detects endogenous levels of total DNAJC3.
    预测反应
    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human DNAJC3, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product DNAJC3 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))
    别名
    DNAJC3 (DNAJC3 产品)
    背景

    Description: Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.

    Gene: DNAJC3

    分子量
    54 kDa
    基因ID
    5611
    UniProt
    Q13217
    途径
    ER-Nucleus Signaling
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