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DNAJC10 抗体 (C-Term)

DNAJC10 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261333
发货至: 中国
  • 抗原 See all DNAJC10 抗体
    DNAJC10 (DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10))
    抗原表位
    • 15
    • 9
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    • 6
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    • 1
    • 1
    • 1
    C-Term
    适用
    • 32
    • 18
    • 4
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 40
    • 4
    克隆类型
    • 41
    • 3
    多克隆
    标记
    • 14
    • 3
    • 3
    • 3
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    • 1
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    This DNAJC10 antibody is un-conjugated
    应用范围
    • 23
    • 20
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    DNAJC10 Antibody detects endogenous levels of total DNAJC10.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human DNAJC10, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product DNAJC10 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    DNAJC10 (DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10))
    别名
    DNAJC10 (DNAJC10 产品)
    别名
    ERdj5 antibody, JPDI antibody, MTHr antibody, PDIA19 antibody, 1200006L06Rik antibody, D2Ertd706e antibody, dnajc10 antibody, zgc:162218 antibody, DnaJ heat shock protein family (Hsp40) member C10 antibody, DnaJ (Hsp40) homolog, subfamily C, member 10 antibody, DNAJC10 antibody, Dnajc10 antibody, dnajc10 antibody
    背景

    Description: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.

    Gene: DNAJC10

    分子量
    75-80 kDa
    基因ID
    54431
    UniProt
    Q8IXB1
    途径
    Cell RedoxHomeostasis
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