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DNAJB14 抗体 (C-Term)

DNAJB14 适用: 人, 大鼠, 小鼠 WB, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261329
发货至: 中国
  • 抗原 See all DNAJB14 抗体
    DNAJB14 (DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14))
    抗原表位
    • 5
    • 1
    • 1
    • 1
    C-Term
    适用
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 10
    克隆类型
    • 10
    多克隆
    标记
    • 6
    • 2
    • 1
    • 1
    This DNAJB14 antibody is un-conjugated
    应用范围
    • 5
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    特异性
    DNAJB14 Antibody detects endogenous levels of total DNAJB14.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human DNAJB14, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product DNAJB14 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    DNAJB14 (DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14))
    别名
    DNAJB14 (DNAJB14 产品)
    别名
    Dnajb14 antibody, MGC153638 antibody, DKFZp468H1319 antibody, EGNR9427 antibody, PRO34683 antibody, 5730496F10Rik antibody, flj14281 antibody, DnaJ heat shock protein family (Hsp40) member B14 antibody, DnaJ (Hsp40) homolog, subfamily B, member 14 antibody, DnaJ heat shock protein family (Hsp40) member B14 S homeolog antibody, DNAJB14 antibody, dnajb14 antibody, Dnajb14 antibody, dnajb14.S antibody
    背景

    Description: Acts as a co-chaperone with HSPA8/Hsc70, required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway (PubMed:24732912). Acts by determining HSPA8/Hsc70's ATPase and polypeptide-binding activities (PubMed:24732912). Can also act independently of HSPA8/Hsc70: together with DNAJB12, acts as a chaperone that promotes maturation of potassium channels KCND2 and KCNH2 by stabilizing nascent channel subunits and assembling them into tetramers (PubMed:27916661). While stabilization of nascent channel proteins is dependent on HSPA8/Hsc70, the process of oligomerization of channel subunits is independent of HSPA8/Hsc70 (PubMed:27916661). When overexpressed, forms membranous structures together with DNAJB12 and HSPA8/Hsc70 within the nucleus, the role of these structures, named DJANGOs, is still unclear (PubMed:24732912).

    Gene: DNAJB14

    分子量
    43 kDa
    基因ID
    79982
    UniProt
    Q8TBM8
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