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DMPK 抗体 (N-Term)

DMPK 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261318
发货至: 中国
  • 抗原 See all DMPK 抗体
    DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
    抗原表位
    • 15
    • 8
    • 7
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    N-Term
    适用
    • 40
    • 21
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 52
    • 5
    克隆类型
    • 54
    • 3
    多克隆
    标记
    • 23
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
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    • 1
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    This DMPK antibody is un-conjugated
    应用范围
    • 30
    • 24
    • 13
    • 13
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    DMPK Antibody detects endogenous levels of total DMPK.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human DMPK, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product DMPK Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
    别名
    DMPK (DMPK 产品)
    别名
    DMPK antibody, DM antibody, DM1 antibody, DM1PK antibody, DMK antibody, MDPK antibody, MT-PK antibody, Dm15 antibody, DM1 protein kinase antibody, dystrophia myotonica-protein kinase antibody, DMPK antibody, Dmpk antibody
    背景

    Description: Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeostasis. Phosphorylates PLN, a regulator of calcium pumps and may regulate sarcoplasmic reticulum calcium uptake in myocytes. May also phosphorylate FXYD1/PLM which is able to induce chloride currents. May also play a role in synaptic plasticity.

    Gene: DMPK

    分子量
    70kDa
    基因ID
    1760
    UniProt
    Q09013
    途径
    Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development
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