COPS8 抗体 (Internal Region)
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- 抗原 See all COPS8 抗体
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
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抗原表位
- Internal Region
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COPS8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- COPS8 Antibody detects endogenous levels of total COPS8.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human COPS8, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product COPS8 Primary Antibody
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anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibody
COPS8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibodyCOPS8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibodyCOPS8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (C-Term) antibodyCOPS8 适用: 人, 大鼠, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (Middle Region) antibodyCOPS8 适用: 人, 大鼠, 小鼠, 马, 兔, Cow, 豚鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibodyCOPS8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 150-198) antibodyCOPS8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (C-Term) antibodyCOPS8 适用: 人, 大鼠, 小鼠, 马, 兔, Cow, 豚鼠, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
- 别名
- COPS8 (COPS8 产品)
- 别名
- COP9 antibody, CSN8 antibody, SGN8 antibody, csn8 antibody, cops8 antibody, MGC76051 antibody, MGC80215 antibody, DDBDRAFT_0167123 antibody, DDBDRAFT_0233107 antibody, DDB_0167123 antibody, DDB_0233107 antibody, zgc:56319 antibody, zgc:86840 antibody, MGC86182 antibody, 9430009J09Rik antibody, AA408242 antibody, Csn8 antibody, Sgn8 antibody, CONSTITUTIVE PHOTOMORPHOGENIC 9 antibody, COP9 SIGNALOSOME SUBUNIT 8 antibody, DL3095C antibody, EMB143 antibody, EMBRYO DEFECTIVE 143 antibody, FCAALL.131 antibody, FUS7 antibody, FUSCA 7 antibody, FUSCA PROTEIN FUS7 antibody, CG13383 antibody, CG33297 antibody, CG42522 antibody, CH8 antibody, Dch8 antibody, Dmel\\CG42522 antibody, Dmel_CG13383 antibody, l(2)SH1829 antibody, l(2)SH2 1829 antibody, COP9 signalosome subunit 8 antibody, COP9 signalosome subunit 8 S homeolog antibody, COP9 signalosome complex subunit 8 antibody, COP9 signalosome subunit 8 L homeolog antibody, COP9 signalosome, subunit CSN8 antibody, COPS8 antibody, Cops8 antibody, cops8 antibody, cops8.S antibody, CSN8 antibody, csn8 antibody, cops8.L antibody, COP9 antibody
- 背景
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Description: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Gene: COPS8
- 分子量
- 23 kDa
- 基因ID
- 10920
- UniProt
- Q99627
- 途径
- Cell Division Cycle
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