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Cofilin 抗体 (N-Term)

CFL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260927
发货至: 中国
  • 抗原 See all Cofilin (CFL1) 抗体
    Cofilin (CFL1) (Cofilin 1 (CFL1))
    抗原表位
    • 18
    • 17
    • 16
    • 15
    • 11
    • 9
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 131
    • 91
    • 89
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 136
    • 9
    • 2
    克隆类型
    • 135
    • 11
    多克隆
    标记
    • 70
    • 10
    • 10
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cofilin antibody is un-conjugated
    应用范围
    • 70
    • 59
    • 44
    • 42
    • 41
    • 41
    • 29
    • 29
    • 16
    • 13
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Cofilin Antibody detects endogenous levels of total Cofilin.
    预测反应
    Pig,Bovine,Horse,Sheep,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human Cofilin, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CFL1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Cofilin (CFL1) (Cofilin 1 (CFL1))
    别名
    CFL1 (CFL1 产品)
    背景

    Description: Binds to F-actin and exhibits  pH -sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity).

    Gene: CFL1

    分子量
    19kDa
    基因ID
    1072
    UniProt
    P23528
    途径
    Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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