CNDP2 抗体 (C-Term)
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- 抗原 See all CNDP2 抗体
- CNDP2 (CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CNDP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- CNDP2 Antibody detects endogenous levels of total CNDP2.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CNDP2, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CNDP2 Primary Antibody
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CNDP2 (CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2))
- 别名
- CNDP2 (CNDP2 产品)
- 别名
- 0610010E05Rik antibody, C76600 antibody, Cn2 antibody, Dip-2 antibody, Pep-1 antibody, Pep1 antibody, CN2 antibody, CPGL antibody, HsT2298 antibody, PEPA antibody, cn2 antibody, cpgl antibody, darmin-r antibody, CNDP2 antibody, zgc:92569 antibody, wu:fd20d11 antibody, wu:fe17f09 antibody, cndp2b antibody, PEPC1 antibody, PEPCase antibody, PPC1 antibody, PPEPC4 antibody, pepc antibody, carnosine dipeptidase 2 antibody, CNDP dipeptidase 2 (metallopeptidase M20 family) antibody, CNDP dipeptidase 2 (metallopeptidase M20 family) S homeolog antibody, CNDP dipeptidase 2 (metallopeptidase M20 family) L homeolog antibody, phosphoenolpyruvate carboxylase 1 antibody, Cndp2 antibody, CNDP2 antibody, cndp2 antibody, cndp2.S antibody, cndp2.L antibody, pep1 antibody
- 背景
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Description: Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly (PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase (MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation (PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells (PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis (PubMed:25964343).
Gene: CNDP2
- 分子量
- 53kDa
- 基因ID
- 55748
- UniProt
- Q96KP4
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