CSNK2A1/CK II alpha 抗体 (N-Term)
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- 抗原 See all CSNK2A1/CK II alpha (CSNK2A1) 抗体
- CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CSNK2A1/CK II alpha antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CKII alpha Antibody detects endogenous levels of total CKII alpha.
- 预测反应
- Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CKII alpha, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CSNK2A1 Primary Antibody
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anti-Casein Kinase 2 alpha 1 (CSNK2A1) (AA 1-100) antibody
CSNK2A1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-Casein Kinase 2 alpha 1 (CSNK2A1) (AA 1-391) antibodyCSNK2A1 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 2 alpha 1 (CSNK2A1) antibodyCSNK2A1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 2 alpha 1 (CSNK2A1) (AA 250-284) antibodyCSNK2A1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB48211 unconjugated
anti-Casein Kinase 2 alpha 1 (CSNK2A1) (AA 201-300) antibodyCSNK2A1 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 2 alpha 1 (CSNK2A1) antibodyCSNK2A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 2 alpha 1 (CSNK2A1) antibodyCSNK2A1 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, Drosophila melanogaster, 猴, Chinook Salmon (Oncorhynchus tschawytscha), 绵羊 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 2 alpha 1 (CSNK2A1) antibodyCSNK2A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Casein Kinase 2 alpha 1 (CSNK2A1) (pTyr255) antibodyCSNK2A1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 2 alpha 1 (CSNK2A1) antibodyCSNK2A1 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 2B6 unconjugated Recombinant Antibody
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- 应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))
- 别名
- CSNK2A1 (CSNK2A1 产品)
- 别名
- CK2A2 antibody, CSNK2A1 antibody, CK2A1 antibody, CKII antibody, CSNK2A3 antibody, CK2A antibody, Ck2a antibody, BmCK2a antibody, wu:fi38e04 antibody, wu:fi38h03 antibody, csnk2a1 antibody, CK-II antibody, CK2 antibody, Ckiialpha antibody, Csnk2a1-rs4 antibody, ck2a1 antibody, casein kinase 2 alpha 2 antibody, casein kinase 2 alpha 1 antibody, casein kinase 2 alpha subunit antibody, casein kinase 2, alpha 1 polypeptide antibody, CK2 protein kinase alpha 2 antibody, casein kinase II alpha subunit antibody, Casein kinase II alpha subunit antibody, casein kinase 2, alpha 1 polypeptide S homeolog antibody, CSNK2A2 antibody, CSNK2A1 antibody, ck2a antibody, Ck2a antibody, csnk2a1 antibody, cka2 antibody, Ckiialpha antibody, CK2A1 antibody, Csnk2a1 antibody, csnk2a1.S antibody
- 背景
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Description: Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Can also negatively regulate apoptosis. Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3. Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8. Regulates transcription by direct phosphorylation of RNA polymerases I, II, III and IV. Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, STAT1, CREB1, IRF1, IRF2, ATF1, SRF, MAX, JUN, FOS, MYC and MYB. Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, which is essential for chaperone function. Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1. Acts as an ectokinase that phosphorylates several extracellular proteins. During viral infection, phosphorylates various proteins involved in the viral life cycles of EBV, HSV, HBV, HCV, HIV, CMV and HPV. Phosphorylates PML at 'Ser-565' and primes it for ubiquitin-mediated degradation. Plays an important role in the circadian clock function by phosphorylating ARNTL/BMAL1 at 'Ser-90' which is pivotal for its interaction with CLOCK and which controls CLOCK nuclear entry (PubMed:11239457, PubMed:11704824, PubMed:16193064, PubMed:19188443, PubMed:20625391, PubMed:22406621). Phosphorylates CCAR2 at 'Thr-454' in gastric carcinoma tissue (PubMed:24962073).
Gene: CSNK2A1
- 分子量
- 45 kDa
- 基因ID
- 1457
- UniProt
- P68400
- 途径
- SARS-CoV-2 Protein Interactome
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