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CISH 抗体 (Internal Region)

CISH 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260845
发货至: 中国
  • 抗原 See all CISH 抗体
    CISH (Cytokine Inducible SH2-Containing Protein (CISH))
    抗原表位
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 24
    • 16
    • 14
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 24
    • 1
    克隆类型
    • 25
    多克隆
    标记
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CISH antibody is un-conjugated
    应用范围
    • 15
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    特异性
    CISH Antibody detects endogenous levels of total CISH.
    预测反应
    Bovine,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CISH, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CISH Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CISH (Cytokine Inducible SH2-Containing Protein (CISH))
    别名
    CISH (CISH 产品)
    别名
    CISH antibody, cis antibody, cish.a antibody, ptk9l antibody, twf1l antibody, wu:fk57g04 antibody, zgc:154062 antibody, zgc:91817 antibody, g18 antibody, socs antibody, cis-1 antibody, cish antibody, BACTS2 antibody, CIS antibody, CIS-1 antibody, G18 antibody, SOCS antibody, AI385595 antibody, CIS1 antibody, Cis antibody, F17 antibody, F23 antibody, cytokine inducible SH2 containing protein antibody, cytokine inducible SH2-containing protein antibody, CISH antibody, cish antibody, Cish antibody
    背景

    Description: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

    Gene: CISH

    分子量
    29kDa
    基因ID
    1154
    UniProt
    Q9NSE2
    途径
    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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