CIDEC 抗体 (Internal Region)
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- 抗原 See all CIDEC 抗体
- CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CIDEC antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- CIDEC Antibody detects endogenous levels of total CIDEC.
- 预测反应
- Horse
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CIDEC, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CIDEC Primary Antibody
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- 应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))
- 别名
- CIDEC (CIDEC 产品)
- 别名
- fsp27 antibody, cide-3 antibody, MGC89274 antibody, cidec antibody, MGC82483 antibody, CIDEC antibody, fd36c01 antibody, wu:fd36c01 antibody, zgc:153033 antibody, CIDE-3 antibody, CIDE3 antibody, FPLD5 antibody, FSP27 antibody, Fsp27 antibody, CIDE-C antibody, cell death inducing DFFA like effector c antibody, cell death inducing DFFA like effector c S homeolog antibody, cell death-inducing DFFA-like effector c antibody, Cell death activator CIDE-3 antibody, cidec antibody, cidec.S antibody, CIDEC antibody, Cidec antibody
- 背景
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Description: Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.
Gene: CIDEC
- 分子量
- 26 kDa
- 基因ID
- 63924
- UniProt
- Q96AQ7
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