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Centriolin 抗体

CNTRL 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260763
发货至: 中国
  • 抗原 See all Centriolin (CNTRL) 抗体
    Centriolin (CNTRL)
    适用
    • 14
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 14
    克隆类型
    • 14
    多克隆
    标记
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Centriolin antibody is un-conjugated
    应用范围
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性
    CEP110 Antibody detects endogenous levels of total CEP110
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CEP110
    亚型
    IgG
  • 应用备注
    WB 1:1000-3000 IHC 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    Centriolin (CNTRL)
    别名
    CEP110 (CNTRL 产品)
    别名
    CEP1 antibody, CEP110 antibody, FAN antibody, bA165P4.1 antibody, Cep1 antibody, Cep110 antibody, 6720467O09Rik antibody, AA968343 antibody, Cntrl antibody, IB3/5 antibody, Ma2a8 antibody, b2b1468Clo antibody, centriolin antibody, CNTRL antibody, Cntrl antibody
    背景

    Description: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).

    Gene: CCP110

    分子量
    113kDa
    基因ID
    9738
    UniProt
    O43303
    途径
    M Phase, SARS-CoV-2 Protein Interactome
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