CDK3 抗体 (C-Term)
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- 抗原 See all CDK3 抗体
- CDK3 (Cyclin-Dependent Kinase 3 (CDK3))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CDK3 Antibody detects endogenous levels of total CDK3.
- 预测反应
- Pig,Bovine,Sheep,Rabbit
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CDK3, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CDK3 Primary Antibody
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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CDK3 is a major target of miR-150 in cell proliferation and anti-cancer effect." in: Experimental and molecular pathology, Vol. 102, Issue 2, pp. 181-190, (2017) (PubMed).
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CDK3 is a major target of miR-150 in cell proliferation and anti-cancer effect." in: Experimental and molecular pathology, Vol. 102, Issue 2, pp. 181-190, (2017) (PubMed).
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- 抗原
- CDK3 (Cyclin-Dependent Kinase 3 (CDK3))
- 别名
- CDK3 (CDK3 产品)
- 别名
- 2310050O10Rik antibody, Cdk3 antibody, cyclin dependent kinase 3 antibody, cyclin-dependent kinase 3 antibody, cyclin-dependent kinase 3, pseudogene antibody, CDK3 antibody, cgd3_1510 antibody, Chro.30182 antibody, Cdk3-ps antibody
- 背景
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Description: Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle, involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.
Gene: CDK3
- 分子量
- 35 kDa
- 基因ID
- 1018
- UniProt
- Q00526
- 途径
- Cell Division Cycle
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