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CD40 Ligand 抗体 (Internal Region)

CD40LG 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260624
发货至: 中国
  • 抗原 See all CD40 Ligand (CD40LG) 抗体
    CD40 Ligand (CD40LG)
    抗原表位
    • 16
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
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    • 1
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    Internal Region
    适用
    • 136
    • 73
    • 35
    • 9
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
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    人, 小鼠
    宿主
    • 85
    • 62
    • 20
    • 15
    • 11
    • 1
    克隆类型
    • 108
    • 80
    • 4
    多克隆
    标记
    • 100
    • 22
    • 20
    • 14
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD40 Ligand antibody is un-conjugated
    应用范围
    • 105
    • 99
    • 54
    • 47
    • 37
    • 30
    • 20
    • 15
    • 14
    • 14
    • 13
    • 13
    • 7
    • 4
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    CD40L Antibody detects endogenous levels of total CD40L.
    预测反应
    Bovine,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CD40L, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CD40LG Primary Antibody
  • 应用备注
    WB 1:1000-3000, IF/ICC 1:200-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CD40 Ligand (CD40LG)
    别名
    CD40LG (CD40LG 产品)
    别名
    CD154 antibody, cd40l antibody, CD40L antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TNFSF5 antibody, TRAP antibody, gp39 antibody, hCD40L antibody, CD40-L antibody, Cd40l antibody, Ly-62 antibody, Ly62 antibody, Tnfsf5 antibody, CD40 ligand antibody, TNF superfamily member 5 antibody, CD40LG antibody, cd40l antibody, Cd40lg antibody
    背景

    Description: Cytokine that binds to CD40/TNFRSF5 (PubMed:1280226). Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (PubMed:8617933). Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28 (PubMed:15067037). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (By similarity).

    Gene: CD40LG

    分子量
    36 kDa
    基因ID
    959
    UniProt
    P29965
    途径
    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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