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CD3 epsilon 抗体 (C-Term)

Name: CD3 epsilon 抗体 (C-Term)
SKU: ABIN6276857
Availability: OutOfStock

CD3E 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of Jurkat, using CD3E antibody. (CD3 epsilon 抗体 (C-Term))

ABIN6276857 at 1/100 staining Human liver cancer tissue by IHC-P. (CD3 epsilon 抗体 (C-Term))

IHC

ABIN6276857 staining HepG2? (CD3 epsilon 抗体 (C-Term))

IF/ICC

Western blot analysis of extracts from rat muscle, using CD3E Antibody. (CD3 epsilon 抗体 (C-Term))

4 images

(1 reference)

产品编号 ABIN6276857

发货至: 中国

Datasheet as PDF

抗原 See all CD3 epsilon (CD3E) 抗体

CD3 epsilon (CD3E)
抗原表位
24

20

16

16

13

12

9

8

6

4

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1
C-Term
适用
216

154

51

42

18

8

8

8

7

4

4

4

4

3

3

3

3

3

3

1

1
人, 小鼠, 大鼠
宿主
133

112

33

23

20

8

1

1

1
兔
Compatible Secondaries
克隆类型
211

115

6
多克隆
标记
122

31

28

20

15

8

8

6

5

4

4

4

4

4

4

4

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This CD3 epsilon antibody is un-conjugated
应用范围
237

135

95

80

70

70

27

27

24

22

14

13

13

12

8

6

4

3

3

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

特异性

CD3 epsilon Antibody detects endogenous levels of total CD3 epsilon.

预测反应

Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human CD3E, corresponding to a region within C-terminal amino acids.

亚型

IgG

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CD3E 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

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anti-CD3 epsilon (CD3E) (AA 23-119) antibody
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anti-CD3 epsilon (CD3E) (AA 156-168), (Cytoplasmic Domain) antibody
CD3E 适用: 人, 大鼠, Pig, 兔, Cow, 马, 豚鼠, 小鸡 FACS, WB, IF 宿主: 小鼠 Monoclonal PC3-188A unconjugated

anti-CD3 epsilon (CD3E) (C-Term) antibody
CD3E 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (C-Term) antibody
CD3E 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 25-207) antibody
CD3E 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 28-185) antibody
CD3E 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 23-207) antibody
CD3E 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Guo, Xue, Li, Yang, Wang, Ma, Zhang, Wang, Zhao, Chang, Chen: "Protective effects of triptolide on TLR4 mediated autoimmune and inflammatory response induced myocardial fibrosis in diabetic cardiomyopathy." in: Journal of ethnopharmacology, Vol. 193, pp. 333-344, (2017) (PubMed).
抗原

CD3 epsilon (CD3E)

别名

CD3E (CD3E 产品)

别名

cd3e antibody, CD3E antibody, t3e antibody, tcre antibody, AI504783 antibody, CD3 antibody, CD3epsilon antibody, T3e antibody, T3E antibody, TCRE antibody, CD3e molecule antibody, CD3 antigen, epsilon polypeptide antibody, cd3e antibody, CD3E antibody, Cd3e antibody

背景

Description: Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways (PubMed:2470098). In addition of this role of signal transduction in T-cell activation, CD3E plays an essential role in correct T-cell developement. Initiates the TCR-CD3 complex assembly by forming the two heterodimers CD3D/CD3E and CD3G/CD3E. Participates also in internalization and cell surface down-regulation of TCR-CD3 complexes via endocytosis sequences present in CD3E cytosolic region (PubMed:10384095, PubMed:26507128).
Gene: CD3E

分子量

23kDa

基因ID

916

UniProt

P07766

途径

TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway