CDK13 抗体 (Internal Region)
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- 抗原 See all CDK13 抗体
- CDK13 (Cyclin-Dependent Kinase 13 (CDK13))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK13 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CD2L5 Antibody detects endogenous levels of total CD2L5.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CD2L5, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CDK13 Primary Antibody
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CDK13 (Cyclin-Dependent Kinase 13 (CDK13))
- 别名
- CDK13 (CDK13 产品)
- 别名
- CDC2L5 antibody, cdc2l5 antibody, wu:fe16d10 antibody, wu:fi49c05 antibody, CDC2L antibody, CHED antibody, hCDK13 antibody, 2310015O17Rik antibody, Cdc2l5 antibody, cyclin dependent kinase 13 antibody, cyclin-dependent kinase 13 antibody, CDK13 antibody, cdk13 antibody, Cdk13 antibody
- 背景
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Description: Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
Gene: CDK13
- 分子量
- 165 kDa
- 基因ID
- 8621
- UniProt
- Q14004
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