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CCDC99 抗体 (C-Term)

CCDC99 适用: 人, 小鼠 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260531
发货至: 中国
  • 抗原 See all CCDC99 抗体
    CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))
    抗原表位
    • 15
    • 9
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 28
    • 16
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 41
    • 3
    克隆类型
    • 42
    • 2
    多克隆
    标记
    • 14
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCDC99 antibody is un-conjugated
    应用范围
    • 19
    • 17
    • 13
    • 13
    • 7
    • 4
    • 3
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    CCDC99 Antibody detects endogenous levels of total CCDC99.
    预测反应
    Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CCDC99, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CCDC99 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))
    别名
    SPDL1 (CCDC99 产品)
    别名
    CCDC99 antibody, CG15415 antibody, Dmel\\CG15415 antibody, SPINDLY antibody, ccdc99 antibody, 1700018I02Rik antibody, 2600001J17Rik antibody, 2810049B11Rik antibody, AA409762 antibody, Ccdc99 antibody, RGD1306908 antibody, ccdc99-a antibody, ccdc99-b antibody, spdl1-a antibody, spdl1-b antibody, spdl1 antibody, spindle apparatus coiled-coil protein 1 antibody, CG15415 gene product from transcript CG15415-RB antibody, Tetratricopeptide repeat (TPR)-like superfamily protein antibody, spindle apparatus coiled-coil protein 1 L homeolog antibody, spindle apparatus coiled-coil protein 1 S homeolog antibody, SPDL1 antibody, Spindly antibody, SPY antibody, spdl1 antibody, Spdl1 antibody, spdl1.L antibody, spdl1.S antibody
    背景

    Description: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment (PubMed:17576797, PubMed:19468067). Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).

    Gene: SPDL1

    分子量
    70kDa
    基因ID
    54908
    UniProt
    Q96EA4
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