CBX6 抗体 (N-Term)
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- 抗原 See all CBX6 抗体
- CBX6 (Chromobox Homolog 6 (CBX6))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBX6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CBX6 Antibody detects endogenous levels of total CBX6.
- 预测反应
- Pig,Bovine,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CBX6, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CBX6 (Chromobox Homolog 6 (CBX6))
- 别名
- CBX6 (CBX6 产品)
- 别名
- cbx6 antibody, CBX6 antibody, zgc:101049 antibody, chromobox 6 antibody, chromobox 6 L homeolog antibody, chromobox homolog 6a antibody, cbx6 antibody, CBX6 antibody, Cbx6 antibody, cbx6.L antibody, cbx6a antibody
- 背景
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Description: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235). Recruitment to chromatin might occur in an H3K27me3-independent fashion (By similarity). May have a PRC1-independent function in embryonic stem cells (By similarity).
Gene: CBX6
- 分子量
- 44kDa
- 基因ID
- 23466
- UniProt
- O95503
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