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Caspase 1 抗体 (C-Term)

CASP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260479
发货至: 中国
  • 抗原 See all Caspase 1 (CASP1) 抗体
    Caspase 1 (CASP1)
    抗原表位
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 93
    • 32
    • 26
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 103
    • 11
    • 3
    • 1
    克隆类型
    • 95
    • 23
    多克隆
    标记
    • 76
    • 19
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Caspase 1 antibody is un-conjugated
    应用范围
    • 91
    • 50
    • 44
    • 20
    • 15
    • 12
    • 11
    • 6
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Caspase 1 Antibody detects endogenous levels of total Caspase 1.
    预测反应
    Pig,Bovine,Rabbit
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human Caspase 1, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CASP1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Caspase 1 (CASP1)
    别名
    CASP1 (CASP1 产品)
    背景

    Description: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive (PubMed:28314590).

    Gene: CASP1

    分子量
    45 kDa 20kDa
    基因ID
    834
    UniProt
    P29466
    途径
    Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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