Casein Kinase 1 gamma 2 抗体 (C-Term)
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- 抗原 See all Casein Kinase 1 gamma 2 (CSNK1G2) 抗体
- Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Casein Kinase 1 gamma 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Casein Kinase Igamma2 Antibody detects endogenous levels of total Casein Kinase Igamma2.
- 预测反应
- Pig,Bovine,Sheep,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Casein Kinase Igamma2, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CSNK1G2 Primary Antibody
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- 应用备注
- WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
- 别名
- CSNK1G2 (CSNK1G2 产品)
- 别名
- CK1g2 antibody, 2810429I12Rik antibody, AI463719 antibody, CKI antibody, ck1-gamma antibody, CSNK1G2 antibody, ck1g2 antibody, csnk1g2 antibody, fj97g11 antibody, wu:fj97g11 antibody, wz8345 antibody, zgc:110719 antibody, zgc:153415 antibody, casein kinase 1 gamma 2 antibody, casein kinase 1, gamma 2 antibody, casein kinase 1 gamma 2 L homeolog antibody, casein kinase 1, gamma 2a antibody, casein kinase 1, gamma 2b antibody, CSNK1G2 antibody, Csnk1g2 antibody, csnk1g2.L antibody, csnk1g2 antibody, csnk1g2a antibody, csnk1g2b antibody
- 背景
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Description: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.
Gene: CSNK1G2
- 分子量
- 47kDa
- 基因ID
- 1455
- UniProt
- P78368
- 途径
- Hedgehog Signaling
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