CARD11 抗体 (Internal Region)
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- 抗原 See all CARD11 抗体
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CARD11 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CARD11 Antibody detects endogenous levels of total CARD11.
- 预测反应
- Pig,Bovine,Horse,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CARD11, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CARD11 Primary Antibody
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
- 别名
- CARD11 (CARD11 产品)
- 背景
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Description: Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. Also activates the TORC1 signaling pathway.
Gene: CARD11
- 分子量
- 133 kDa
- 基因ID
- 84433
- UniProt
- Q9BXL7
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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