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CAMSAP2 抗体 (C-Term)

CAMSAP1L1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260440
发货至: 中国
  • 抗原 See all CAMSAP2 (CAMSAP1L1) products
    CAMSAP2 (CAMSAP1L1) (Calmodulin Regulated Spectrin-associated Protein 1-like 1 (CAMSAP1L1))
    抗原表位
    • 2
    • 1
    • 1
    C-Term
    适用
    • 6
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 6
    克隆类型
    • 6
    多克隆
    标记
    • 6
    This CAMSAP2 antibody is un-conjugated
    应用范围
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    CAMSAP2 Antibody detects endogenous levels of total CAMSAP2.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CAMSAP2, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CAMSAP2 (CAMSAP1L1) (Calmodulin Regulated Spectrin-associated Protein 1-like 1 (CAMSAP1L1))
    别名
    CAMSAP2 (CAMSAP1L1 产品)
    别名
    Camsap1l1 antibody, RGD1310950 antibody, camsap1l1 antibody, si:dkey-39e8.1 antibody, wu:fc16g04 antibody, wu:fc23h08 antibody, CAMSAP1L1 antibody, 1600013L13Rik antibody, 4930541M15Rik antibody, mKIAA1078 antibody, calmodulin regulated spectrin-associated protein family, member 2 antibody, calmodulin regulated spectrin associated protein family member 2 antibody, calmodulin regulated spectrin-associated protein family, member 2a antibody, Camsap2 antibody, CAMSAP2 antibody, camsap2a antibody, camsap2 antibody
    背景

    Description: Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization (PubMed:23169647, PubMed:24486153, PubMed:24706919). Specifically recognizes growing microtubule minus-ends and autonomously decorates and stabilizes microtubule lattice formed by microtubule minus-end polymerization (PubMed:24486153, PubMed:24706919). Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization (PubMed:24486153, PubMed:24706919). In addition, it also reduces the velocity of microtubule polymerization (PubMed:24486153, PubMed:24706919). Through the microtubule cytoskeleton, also regulates the organization of cellular organelles including the Golgi and the early endosomes (PubMed:27666745). Essential for the tethering, but not for nucleation of non-centrosomal microtubules at the Golgi: together with Golgi-associated proteins AKAP9 and PDE4DIP, required to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (PubMed:27666745). Also acts as a regulator of neuronal polarity and development: localizes to non-centrosomal microtubule minus-ends in neurons and stabilizes non-centrosomal microtubules, which is required for neuronal polarity, axon specification and dendritic branch formation (PubMed:24908486). Through the microtubule cytoskeleton, regulates the autophagosome transport (PubMed:28726242).

    Gene: CAMSAP2

    分子量
    168 kDa
    基因ID
    23271
    UniProt
    Q08AD1
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