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CALCOCO2 抗体 (Internal Region)

CALCOCO2 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260408
发货至: 中国
  • 抗原 See all CALCOCO2 抗体
    CALCOCO2 (Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2))
    抗原表位
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Internal Region
    适用
    • 28
    • 4
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 18
    • 11
    克隆类型
    • 20
    • 9
    多克隆
    标记
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CALCOCO2 antibody is un-conjugated
    应用范围
    • 22
    • 10
    • 6
    • 6
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    特异性
    CALCOCO2 Antibody detects endogenous levels of total CALCOCO2.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CALCOCO2, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CALCOCO2 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CALCOCO2 (Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2))
    别名
    CALCOCO2 (CALCOCO2 产品)
    别名
    CALCOCO2 antibody, MGC110205 antibody, wu:fj08c01 antibody, zgc:110205 antibody, DKFZp469D2219 antibody, NDP52 antibody, 2410154J16Rik antibody, C77254 antibody, Ndp52 antibody, Ndp52l1 antibody, RGD1559974 antibody, calcium binding and coiled-coil domain 2 antibody, CALCOCO2 antibody, calcoco2 antibody, Calcoco2 antibody
    背景

    Description: Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation. Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens such as Salmonella typhimurium upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (PubMed:22246324). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation (PubMed:23022382, PubMed:25771791). Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A, MAP1LC3B and/or GABARAPL2, whereas regulation of pathogen-containing autophagosome maturation requires the interaction with MAP3LC3C (PubMed:23022382, PubMed:25771791). May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion (PubMed:17635994).

    Gene: CALCOCO2

    分子量
    52 kDa
    基因ID
    10241
    UniProt
    Q13137
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