BNIP3L/NIX 抗体 (Internal Region)
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- 抗原 See all BNIP3L/NIX (BNIP3L) 抗体
- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BNIP3L/NIX antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- BNIP3L Antibody detects endogenous levels of total BNIP3L.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human BNIP3L, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product BNIP3L Primary Antibody
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
- 别名
- BNIP3L (BNIP3L 产品)
- 别名
- BNIP3a antibody, NIX antibody, NIP3 antibody, Nix antibody, Nip3 antibody, C86132 antibody, D14Ertd719e antibody, Nip3L antibody, bnip3l antibody, nip3 antibody, zgc:110478 antibody, bnip3l2 antibody, wu:fb52b03 antibody, wu:fc02h04 antibody, BCL2 interacting protein 3 like antibody, BCL2 interacting protein 3 antibody, BCL2/adenovirus E1B interacting protein 3 antibody, BCL2/adenovirus E1B interacting protein 3-like antibody, BCL2/adenovirus E1B interacting protein 3-like b antibody, BCL2/adenovirus E1B interacting protein 3-like a antibody, BNIP3L antibody, BNIP3 antibody, Bnip3l antibody, Bnip3 antibody, bnip3lb antibody, bnip3la antibody
- 背景
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Description: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
Gene: BNIP3L
- 分子量
- 35 kDa
- 基因ID
- 665
- UniProt
- O60238
- 途径
- Autophagy
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