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- 抗原 See all BBS2 抗体
- BBS2 (Bardet-Biedl Syndrome 2 (BBS2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BBS2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- BBS2 Antibody detects endogenous levels of total BBS2.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human BBS2, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product BBS2 Primary Antibody
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anti-Bardet-Biedl Syndrome 2 (BBS2) (AA 1-96) antibody
BBS2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) antibodyBBS2 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) (AA 1-721) antibodyBBS2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) (AA 151-200) antibodyBBS2 适用: 人, 犬, 马, 兔, 斑马鱼, Cow, 豚鼠, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) (AA 315-364) antibodyBBS2 适用: 人, 小鼠, 犬, 马, 兔, 斑马鱼, Cow, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) (N-Term) antibodyBBS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) (N-Term) antibodyBBS2 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 斑马鱼, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- BBS2 (Bardet-Biedl Syndrome 2 (BBS2))
- 别名
- BBS2 (BBS2 产品)
- 别名
- fb80a05 antibody, wu:fb80a05 antibody, DKFZp468B105 antibody, DKFZp469L0919 antibody, BBS antibody, 2410125H22Rik antibody, AI447581 antibody, Bardet-Biedl syndrome 2 antibody, bardet-biedl syndrome 2 antibody, Bardet-Biedl syndrome 2 (human) antibody, bbs2 antibody, BBS2 antibody, Bbs2 antibody
- 背景
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Description: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
Gene: BBS2
- 分子量
- 80 kDa
- 基因ID
- 583
- UniProt
- Q9BXC9
- 途径
- Hedgehog Signaling
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